SOS!!! PLEASE HELP!!! NEUROLOGICAL MESS--UNEXPLAINED SPASTICITY--LOSING MOBILITY!!!!! About 5 years my husband started on lisinopril and began with with burning feet which progressed to tight muscles in his calfs and then progressed to his thighs and trunk. This tightness (spasticity) includes brisk reflexes. Recently he has lost his grip with his hands and now has the spasticity in his arms. It is very difficult to walk. 3 months after taking lisinopril the symptoms began and he got off the med. There were no changes however, symptoms did not progress, so he got back on for 5 years until a 4 months ago. Now no increase in disease however, no reverse either. Lisinopril is made from snake venom! Anyone out there who can help--do you think this is lisinopril? How can we find out? We've been in and out of Boston/Providence to the best neuro doctors in history and nobody has any answers as to why this is happening to him. 5 MRI's 4 spinal taps and nothing turns up.
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